Future Inns is planning to open its new £20-million hotel by the beginning of May and bookings are already being taken.
The Canadian-based chain says its Cabot Circus hotel is a statement of its commitment to expand in the South West despite the recession.
The hotel will include a jazz club and conference facilities on the top floor for up to 400 people, with panoramic city views.
Future Inns managing director Del Brett said: “We are now recruiting for the right people who can fulfil our commitment to the highest quality and service standards.”